






Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog’s entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.
Is Discontinued By Manufacturer : No
Product Dimensions : 5.75 x 0.75 x 4.5 inches; 1.6 ounces
Manufacturer recommended age : 1 month and up
Item model number : 72220
Department : Flea & Tick
Date First Available : May 30, 2004
Manufacturer : Boehringer Ingelheim Animal Health
ASIN : B0002J1FP8
Best Sellers Rank: #1,429 in Pet Supplies (See Top 100 in Pet Supplies) #10 in Dog Flea Drops
Customer Reviews: 4.4 4.4 out of 5 stars 14,979 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
9 reviews for FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments
Add a review
$27.99

Veronica –
frontline
this frontline works very well on all my dogs i will always use this product. it’s easy to apply on my dogs
Amazon Customer –
Works
Must have for outside dogs.
Dale Harper –
.
handy to have when needed
D S –
Many uses- goat & swine mange, chicken mites, dogs.
Fantastic for feather and leg mites in chickens, scales start falling off within days, can take a few treatments for bad infestations. Slather with neem oil also to suffocate the mites between treatments. A lot of vets recommend this off label for mange in goats, swine and camelids and it works wonderfully. Treat, then treat again in 2-4 weeks. Hair starts growing back within a few days. In 2 weeks you can hardly tell but treat again or the mites come back since the eggs are hatching- get them on a mineral buffet as well so they can balance their systems and immunity to pests. However it is not lasting the 30 days it used to for fleas in dogs. Fleas were gone for about a week after treatment. Then one or 2 started appearing again. I am going to treat dogs for fleas every 2 weeks.This is the reason for 4 stars. I buy this plus size to treat 4 small 25lb dogs. It works great for chicken leg mites and feather mites, youtube videos show you how to apply, a drop on each leg, around vent, back of neck etc. Fantastic for mange in goats and llamas- use the same weight used for a dog.
Jack –
A must have for my dogs
I have been using Frontline for years and will continue to do so. The ease of application and the protection it provides has been favored by me and my dogs. I usually by a 3 month supply for each of my dogs. It is becomes clear if I forget to give it my dogs. In my opinion each dose does last almost exactly one month. Usually I will notice the dogs starting to scratch if I forget. As soon as I apply, by the end of the day, the scratching will stop. I love knowing my dogs are protected. I have a lot of stray cats that invade my yard and they always carry fleas so knowing my dogs get what they need to reduce the fleas is essential.To apply, I break of the top of each little vial and apply directly on the skin above their shoulders. The dogs dont even notice. It is very easy. My dogs don’t like taking anything in a pill form and just spit them out, so having this where I apply topical is better for me.I highly recommend. This product works and I don’t think you will be disappointed. I will add to make sure you use the right product which is determined by the weight of your pet. I don’t know, nor do I want to find out if I give my 70lb dog the same product as my 120lb. Just buy the one that is designed for the weight of your dog. Other than that, I highly recommend.
JR –
No fleas or ticks
I have not found any ticks or fleas on my pups and have been using this brand for years. No skin irritations or adverse reactions.
Amie Kennedy –
Good product
Product works well, I live in Florida, off grid, in the woods. We have lots of sand, and my lab is active and always playing in the forest. I never have problems with ticks or fleas. Nats are still a pain, but I use Avons, Skin So Soft, I spray it on my hands, lightly pass over her eyes, back and tail. I’ve never seen skin or eye irritation from any of my dogs. From the flea control or the Skin so soft. Hope this helps.
5550 –
WASTE OF MONEY DOESN’T WORK!!!!
Since application I have literally pulled off seven ticks. Some attached some crawling to attach. Literally pulled two off within 6 hours of application. The rest have been within the last week. We have Lyme disease here. This was the reason why I got this. If my dog ends up with Lyme disease you’ll end up with a bill!! I want my money back. Don’t listen to their money back. Guarantee you call that number on the back of the box and they just want to find all sorts of loopholes of reasons. Why not to give you your money back. They want ticks to eat on your dog up to 3 months! It doesn’t matter where I purchased it. The facts are the facts. It does not work! seven ticks 3 weeks. Says “kills ticks including those that may transmit Lyme disease” when you talk to the company they say it doesn’t protect against Lyme disease! Fair the definition of what’s wrong with companies finding loopholes to basically screw over their customers.
Zee –
It says there is 6 doses inside but i received only 3 and package was opened!